castanyes blaves

MEFIT - Complex human diseases analysed at a meta-study level for gene expression datasets

Interests:
Gene     -> Function
Gene     -> Gene
Data     -> Function
Function -> Function e.g. regulatory cross-talk

Prior knowledge on yeast ~80% whereas human is less than 40%

Sleipnip - 8 hours to 1 minute in yeast -- 30 years to 2 months - 18 hours in parallel

Predicted functional relatedness of a gene against any other gene in the genome

What is the data that relates BRCA1 and BRCA2? Mint, BioGRID, etc.

Genes that are related to a known disease, eg. altzheimer's disease

Is a gene performing X specific function to another group of genes?