castanyes blaves

Random ramblings about some random stuff, and things; but more stuff than things -- all in a mesmerizing and kaleidoscopic soapbox-like flow of words.

5/30/2008

 

Ensembl GeneTree for CTNNBL1: a novel gene for obesity

CTNNBL1 (Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)) is a gene recently linked to obesity (HMG).

The domain structure shows an "Armadillo" SMART domain and a shorter PFAM domain
at the beginning of the protein:



The Ensembl Compara GeneTree for CTNNBL1 shows:



A high degree of conservation across a wide range of species, down to the nematode C. elegans. We unfortunately
have partial predictions for platypus, and a suspiciously partial prediction for cow, as well as the cat and shrew 2x genomes.

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