The Consensus CoDing Sequence (CCDS) project is a collaborative effort to identify a core set of human protein-coding regions that are consistently annotated and of high quality. The long-term goal is to support convergence toward a standard set of gene annotations on the human genome.
Annotation of genes on the human genome is provided by multiple public resources using different methods, resulting in information that is similar but not always identical. The human genome sequence is now sufficiently stable to start identifying gene placements that are identical, and making this data public and supported as a core set by the three major public human genome browsers. The long-term goal is to support convergence towards a standard set of gene annotations on the human genome.
Toward this end, the Consensus CDS (CCDS) project was established. The CCDS project is a collaborative effort to identify a core set of human protein-coding regions that are consistently annotated and of high quality.
The initial CCDS data set, containing nearly 15,000 genes, has been posted
on three Internet sites:
- the UCSC Genome Browser (http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg17)
- the Ensembl Genome Browser (http://www.ensembl.org/)
- the NCBI CCDS Database website (http://www.ncbi.nlm.nih.gov/CCDS/)
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